Blar i Brage IMR på forfatter "Lille-Langøy, Roger"
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Agonistic and potentiating effects of perfluoroalkyl substances (PFAS) on the Atlantic cod (Gadus morhua) peroxisome proliferator-activated receptors (Ppars)
Söderström, Sofie Karin; Lille-Langøy, Roger; Yadetie, Fekadu; Rauch, Mateusz; Milinski, Ana; Dejaegere, Annick; Stote, Roland H.; Goksøyr, Anders; Karlsen, Odd André (Peer reviewed; Journal article, 2022)Toxicity mediated by per- and polyfluoroalkyl substances (PFAS), and especially perfluoroalkyl acids (PFAAs), has been linked to activation of peroxisome proliferator-activated receptors (Ppar) in many vertebrates. Here, ... -
Genetics in the ocean’s twilight zone: Population structure of the glacier lanternfish across its distribution range
Quintela, Maria; Garcia-Seoane, Eva; Dahle, Geir; Klevjer, Thor A.; Melle, Webjørn; Lille-Langøy, Roger; Besnier, Francois; Tsagarakis, Konstantinos; Geoffroy, Maxime; Rodríguez-Ezpeleta, Naiara; Jacobsen, Eugenie; Côté, David; Knutar, Sofie; Unneland, Laila; Strand, Espen; Glover, Kevin (Dataset, 2024)Dataset for "Genetics in the ocean’s twilight zone: Population structure of the glacier lanternfish across its distribution range", published in Evolutionary Applications, a Wiley journal The information deposited ... -
Polycyclic aromatic hydrocarbons modulate the activity of Atlantic cod (Gadus morhua) vitamin D receptor paralogs in vitro
Goksøyr, Siri Øfsthus; Goldstone, Jed; Lille-Langøy, Roger; Lock, Erik Jan Robert; Olsvik, Pål Asgeir; Goksøyr, Anders; Karlsen, Odd André (Peer reviewed; Journal article, 2021)Vitamin D receptor (VDR) mediates the biological function of the steroid hormone calcitriol, which is the metabolically active version of vitamin D. Calcitriol is important for a wide array of physiological functions, ... -
Proteomics and lipidomics analyses reveal modulation of lipid metabolism by perfluoroalkyl substances in liver of Atlantic cod (Gadus morhua)
Dale, Karina; Yadetie, Fekadu; Müller, Mette Helen Bjørge; Pampanin, Daniela Maria; Gilabert, Alejandra; Zhang, Xiaokang; Tairova, Zhanna; Haarr, Ane; Lille-Langøy, Roger; Lyche, Jan Ludvig; Porte, Cinta; Karlsen, Odd Andre; Goksøyr, Anders (Peer reviewed; Journal article, 2020)The aim of the present study was to investigate effects of defined mixtures of polycyclic aromatic hydrocarbons (PAHs) and perfluoroalkyl substances (PFASs), at low, environmentally relevant (1× = L), or high (20× = H) ... -
Xenobiotic metabolism and its physiological consequences in high-Antarctic Notothenioid fishes
Strobel, Anneli; Lille-Langøy, Roger; Segner, Helmut; Burkhardt-Holm, Patricia; Goksøyr, Anders; Karlsen, Odd André (Peer reviewed; Journal article, 2021)The Antarctic ecosystem is progressively exposed to anthropogenic contaminants, such as polycyclic aromatic hydrocarbons (PAHs). So far, it is largely unknown if PAHs leave a mark in the physiology of high-Antarctic fish. ...